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Cyclophosphamide


Table of Contents


Cyclophosphamide

Examples

Generic NameBrand Name
cyclophosphamideCytoxan

How It Works

Cyclophosphamide is an alkylating agent and is related to mustard gas. It causes cell death by interfering with the way genetic material (DNA) in the cell multiplies.

Cyclophosphamide is available as an intravenous (IV) medicine and as tablets for oral use in 25 mg and 50 mg. The type and extent of a disease and your body size determine the exact dose and schedule of administering this medicine.

Why It Is Used

Cyclophosphamide is used to treat many forms of cancer, including:

Cyclophosphamide is also used to treat other diseases, such as:

Cyclophosphamide is often used before a bone marrow transplant or after another type of transplant, such as a kidney or liver transplant.

How Well It Works

Cyclophosphamide treats many forms of cancer. It is usually combined with other chemotherapy medicines but may be used alone.

Side Effects

Side effects with cyclophosphamide may include:

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Cyclophosphamide should be given only under the supervision of a medical oncologist.

Cyclophosphamide can affect your ability to have children. You may not be able to become pregnant or father a child after taking cyclophosphamide. Discuss fertility with your doctor before starting treatment with this drug.

Cyclophosphamide can cause birth defects. Do not use this medicine if you are pregnant or wish to become pregnant or father a child while you are taking it.

Women who take this medicine may experience menopausal symptoms, including hot flashes and vaginal dryness.

Complete the new medication information form (PDF) to help you understand this medication.

Credits for Cyclophosphamide

By Healthwise Staff
Primary Medical Reviewer Sarah Marshall, MD - Family Medicine
Specialist Medical Reviewer Douglas A. Stewart, MD - Medical Oncology
Last Revised June 28, 2013

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